Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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345
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331
Tocris Bioscience™ Betulinic acid
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 472-15-1 Molecular Formula: C30H48O3
| CAS | 472-15-1 |
|---|---|
| Molecular Formula | C30H48O3 |
332
Tocris Bioscience™ 5,7-Dichlorokynurenic acid sodium salt
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Sodium salt of 5,7-Dichlorokynurenic acid (Cat. No. 0286). Potent NMDA antagonist, acts at glycine site
| Inhibitors | 5,7-Dichlorokynurenic acid sodium salt |
|---|---|
| Product Type | 5,7-Dichlorokynurenic acid sodium salt |
| Molecular Weight (g/mol) | 280.04 |
| Purity | >98% |
333
Tocris Bioscience™ BMS 345541
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Selective allosteric inhibitor of IKK; anti-inflammatory
| Inhibitors | BMS 345541 |
|---|---|
| Product Type | BMS 345541 |
| Molecular Weight (g/mol) | 291.78 |
| Purity | >99% |
334
Tocris Bioscience™ FITC
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Green fluorescent dye
335
Tocris Bioscience™ Pyrimethamine
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CAS: 58-14-0 Molecular Formula: C12H13ClN4
| CAS | 58-14-0 |
|---|---|
| Molecular Formula | C12H13ClN4 |
336
Tocris Bioscience™ TC LPA5 4
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CAS: 1393814-38-4 Molecular Formula: C23H23ClN2O3
| CAS | 1393814-38-4 |
|---|---|
| Molecular Formula | C23H23ClN2O3 |
337
Tocris Bioscience™ JP-2-196 alkyne
RNF126 chemical handle; alkyne functionalized version of JP-2-196 (Cat. No. 8046).
338
Tocris Bioscience™ M8 B hydrochloride
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Potent and selective TRPM8 channel blocker
| Inhibitors | M8 B hydrochloride |
|---|---|
| Product Type | M8 B hydrochloride |
| Molecular Weight (g/mol) | 432.96 |
| Purity | >99% |
339
Tocris Bioscience™ Hoechst Janelia Fluor 526
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Fluorogenic, green-emitting DNA probe
340
Tocris Bioscience™ PCI 29732
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent BTK inhibitor
| Inhibitors | PCI 29732 |
|---|---|
| Product Type | PCI 29732 |
| Molecular Weight (g/mol) | 371.44 |
| Purity | >99% |
341
Tocris Bioscience™ GSK J1
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 1373422-53-7 Molecular Formula: C22H23N5O2
| CAS | 1373422-53-7 |
|---|---|
| Molecular Formula | C22H23N5O2 |
342
Tocris Bioscience™ OB 24 hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective heme oxygenase 1 (HO-1) inhibitor
| CAS | 939825-12-4 |
|---|---|
| Chemical Name or Material | 1-[[2-[2-(4-Bromophenyl)ethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazole hydrochloride |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C15H17BrN2O2.HCl |
| Formula Weight | Observed MW: 373.67 |
| Assay Percent Range | >98% |
343
Tocris Bioscience™ NS 8593 Hydrochloride
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Selective negative modulator of KCa2 (SK) channels; inhibits SK currents
| CAS | 875755-24-1 |
|---|---|
| Product Type | Bioactive Small Molecule |
| Solubility | Soluble to 100mM in DMSO and to 20mM in ethanol |
| Purity | >98% |
| Physical Form | Solid |
| Chemical Name or Material | NS 8593 hydrochloride |
| Recommended Storage | Store at 4°C |
| Synonym | N-[(1R)-1,2,3,4-Tetrahydro-1-naphthalenyl]-1H-benzimidazol-2-amine hydrochloride |
| Molecular Formula | C17H17N3·HCl |
| Formula Weight | 299.8 |
344
Tocris Bioscience™ SR 13800
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent MCT1 inhibitor
| Target | Monocarboxylate Transporter Inhibitors |
|---|---|
| CAS | 227321-12-2 |
| Purity | >98% |
| Chemical Name or Material | 2,6-Dihydro-7-[(3-hydroxypropyl)thio]-2-methyl-4-(2-methylpropyl)-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyridazin-1one |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C25H29N3O2S |
| Formula Weight | 435.58 |
345
Tocris Bioscience™ BIO
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 667463-62-9 Molecular Formula: C16H10BrN3O2
| CAS | 667463-62-9 |
|---|---|
| Molecular Formula | C16H10BrN3O2 |